Vaccines are in the news! Hooray for scientists! But how do vaccines work?
How does your body fight disease?
When germs such as bacteria or viruses infect your body, they attack and multiply which causes illness.
Your immune system’s job is to fight the bacteria or virus. You have three different types of white blood cells who all work together to eliminate the germ.
One type of white blood cell is called a macrophage. Macrophages surround and digest germs, leaving behind proteins that the germ contained called antigens. Antigens are proteins that are specific for each germ. T-lymphocytes are white blood cells that attack your own cells after they have been infected so they can’t reproduce. B-lymphocytes are white blood cells that produce antibodies to attack the antigen. The B-lymphocytes have the ability to recognize antigens after they have seen them which makes the antibody production much faster the second time you are exposed to the same germ.
Herd immunity
Vaccinations help more people than just the patient who receives the vaccine. Very young babies or people with weaker immune systems may not be able to receive vaccines which would make them very vulnerable if they were exposed to a serious disease. Vaccinating everyone around them, even if the disease might not hurt the other people, creates a population of people that can’t be infected which means they can’t pass the bacteria or virus on to the people with weak immune systems. This is called herd immunity and it is one of the reasons why schoolchildren are required to have vaccines.
How do vaccines help your immune system?
Vaccines cause your body to produce antibodies against a particular germ. Chickenpox vaccines, for example, cause your body to produce antibodies against the chickenpox antigen. Once your body has been exposed to an antigen, it remembers it and is able to produce antibodies quickly if you get exposed to it a second time. This prevents the germ from being able to infect you later. For diseases that are very serious, this quicker immune response can save your life.
The flu vaccine
Seasonal influenza is caused by a highly contagious virus and can be serious in some people. Many physicians recommend an annual flu vaccine. But why do people need to have a vaccine every year if the body’s immune system can remember an antigen? The reason for this is that the flu virus mutates quickly which causes new strains of virus every year. So even if you had immunity to last year’s virus, this year’s might be very different and your antibodies likely won’t respond to this year’s antigens. Even if you get the flu vaccine this year, you still might get the flu for a few reasons. First, if you are exposed to the flu soon after getting the vaccine, your body may not have had time to build up a stockpile of antibodies. For another reason, you may get a version of the flu that wasn’t in your vaccine.
Side effects of vaccines
Because some vaccines contain weakened forms of the germ, people may experience some mild symptoms after receiving the vaccine. Activating B-lymphocytes may cause a low grade fever and some achiness for a day or two.
Anti-Vaxxers
In 1995, a physician named Andrew Wakefield speculated that vaccines cause autism. Not only were the number of children diagnosed with autism increasing, the number of vaccines children were given was increasing. Dr. Wakefield studied 12 children who had been vaccinated and were diagnosed with autism and concluded that the vaccine had caused the autism. His conclusion was widely published and caused the beginning of what is sometimes called the anti-vaxxer movement. Anti-vaxxers believe that vaccines cause diseases, including autism, and choose not to vaccinate their children.
The findings of Dr. Wakefield have been completely refuted by multiple scientific studies covering 1.2 million children. The studies conclude that there is no relationship between vaccination and autism.
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